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Motif ID: TLX1..3_NFIC{dimer}.p2

Z-value: 3.713

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr9_+_139872014	140.213		PTGDS	prostaglandin D2 synthase 21kDa (brain)
chr16_+_222845	109.580	NM_000517	HBA1 HBA2	hemoglobin, alpha 1 hemoglobin, alpha 2
chr16_+_226678	102.072	NM_000558	HBA1 HBA2	hemoglobin, alpha 1 hemoglobin, alpha 2
chr9_+_139871954	99.060	NM_000954	PTGDS	prostaglandin D2 synthase 21kDa (brain)
chr18_-_74729049	71.449	NM_001025081 NM_001025090 NM_001025092 NM_002385	MBP	myelin basic protein
chr18_-_74728963	69.730		MBP	myelin basic protein
chr2_-_218843541	60.699		TNS1	tensin 1
chr12_-_56106061	54.937	NM_001144997	ITGA7	integrin, alpha 7
chr17_-_42992852	52.843	NM_001131019 NM_001242376 NM_002055	GFAP	glial fibrillary acidic protein
chrX_-_13956530	49.755		GPM6B	glycoprotein M6B
chr2_-_217560247	48.949	NM_000599	IGFBP5	insulin-like growth factor binding protein 5
chr10_+_106034886	48.478	NM_001191014 NM_001191015	GSTO2	glutathione S-transferase omega 2
chrX_-_13956445	44.393
chr3_-_58563070	44.265		FAM107A	family with sequence similarity 107, member A
chr8_-_80679897	41.981	NM_001040708 NM_012258	HEY1	hairy/enhancer-of-split related with YRPW motif 1
chr6_+_150920998	41.750	NM_001029884	PLEKHG1	pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr17_-_66951381	38.848	NM_007168	ABCA8	ATP-binding cassette, sub-family A (ABC1), member 8
chr3_-_195306274	38.128		APOD	apolipoprotein D
chr9_+_124086842	37.971		GSN	gelsolin
chr17_-_15164043	37.395	NM_153322	PMP22	peripheral myelin protein 22
chr21_+_46875402	34.560	NM_030582	COL18A1	collagen, type XVIII, alpha 1
chrX_-_13956644	33.651	NM_001001994	GPM6B	glycoprotein M6B
chr16_-_2264776	33.404	NM_001042371	PGP	phosphoglycolate phosphatase
chr7_-_27187367	33.175	NM_024014	HOXA6	homeobox A6
chr9_-_79520878	32.779	NM_015225	PRUNE2	prune homolog 2 (Drosophila)
chr2_+_66662516	32.395	NM_002398	MEIS1	Meis homeobox 1
chr11_+_46722564	32.174	NM_001184751	ZNF408	zinc finger protein 408
chrX_-_133119475	32.024		GPC3	glypican 3
chr11_-_62457001	31.450		LRRN4CL	LRRN4 C-terminal like
chr5_+_72251869	30.155
chr12_+_57522247	29.850	NM_002332	LRP1	low density lipoprotein receptor-related protein 1
chr9_-_23821808	29.612		ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr10_-_128077062	29.590		ADAM12	ADAM metallopeptidase domain 12
chr10_-_105452878	29.559		SH3PXD2A	SH3 and PX domains 2A
chrX_+_46937807	29.484		RGN	regucalcin (senescence marker protein-30)
chr10_+_17271302	28.949		VIM	vimentin
chr6_-_46922533	28.553	NM_015234	GPR116	G protein-coupled receptor 116
chr17_+_27369917	28.267	NM_016518	PIPOX	pipecolic acid oxidase
chrX_+_46937889	28.246		RGN	regucalcin (senescence marker protein-30)
chr12_+_119616594	28.121	NM_014365	HSPB8	heat shock 22kDa protein 8
chrX_+_46937744	28.108	NM_004683 NM_152869	RGN	regucalcin (senescence marker protein-30)
chrX_-_133119624	28.044	NM_001164617 NM_001164618 NM_001164619 NM_004484	GPC3	glypican 3
chr10_+_17271277	28.036		VIM	vimentin
chr5_+_150020201	28.030	NM_001109974 NM_007286	SYNPO	synaptopodin
chr9_-_13279562	28.010		MPDZ	multiple PDZ domain protein
chrX_-_53310748	27.593	NM_001243197 NM_015075	IQSEC2	IQ motif and Sec7 domain 2
chr5_-_172198160	27.575	NM_004417	DUSP1	dual specificity phosphatase 1
chr19_+_15783827	27.515	NM_023944	CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12
chr15_-_65503786	27.195	NM_003613	CILP	cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr9_-_23821842	27.147	NM_001171195	ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr2_+_66662692	26.883		MEIS1	Meis homeobox 1
chr21_-_28217272	26.863		ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr19_+_58111244	26.819	NM_020880	ZNF530	zinc finger protein 530
chr7_+_102553343	26.439	NM_001031692 NM_005824	LRRC17	leucine rich repeat containing 17
chr1_+_22979681	26.346	NM_000491	C1QB	complement component 1, q subcomponent, B chain
chr9_-_130616957	25.945		ENG	endoglin
chr17_+_38599651	25.804	NM_001552	IGFBP4	insulin-like growth factor binding protein 4
chr6_+_29555682	25.579	NM_007160	OR2H2	olfactory receptor, family 2, subfamily H, member 2
chr10_+_17271341	25.579		VIM	vimentin
chr6_-_31745048	25.119	NM_025258	C6orf27	chromosome 6 open reading frame 27
chr11_-_62457370	24.694	NM_203422	LRRN4CL	LRRN4 C-terminal like
chr10_+_17271276	24.623		VIM	vimentin
chr3_-_14989399	24.409		LOC100505641	uncharacterized LOC100505641
chr9_-_130616592	24.286		ENG	endoglin
chr14_-_76448091	24.079	NM_003239	TGFB3	transforming growth factor, beta 3
chr22_+_21986968	23.970	NM_152612	CCDC116	coiled-coil domain containing 116
chr4_-_48014960	23.936	NM_000087	CNGA1	cyclic nucleotide gated channel alpha 1
chr17_+_27370155	23.545		PIPOX	pipecolic acid oxidase
chr22_+_33196801	23.523	NM_000362	TIMP3	TIMP metallopeptidase inhibitor 3
chr8_-_82395401	23.447	NM_001442	FABP4	fatty acid binding protein 4, adipocyte
chr21_-_28217692	23.347	NM_006988	ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr19_+_16222706	23.096		RAB8A	RAB8A, member RAS oncogene family
chr9_+_124043719	22.869		GSN	gelsolin
chr21_+_47531369	22.825		COL6A2	collagen, type VI, alpha 2
chr12_+_54332575	22.660	NM_017410	HOXC13	homeobox C13
chr19_+_50936159	22.446	NM_004533	MYBPC2	myosin binding protein C, fast type
chr8_-_42065193	22.264	NM_000930 NM_033011	PLAT	plasminogen activator, tissue
chr9_+_102584136	22.126	NM_006981 NM_173199 NM_173200	NR4A3	nuclear receptor subfamily 4, group A, member 3
chr8_+_24772454	22.024	NM_001105541	NEFM	neurofilament, medium polypeptide
chr9_-_130616760	21.731		ENG	endoglin
chr20_+_56136136	21.618	NM_002591	PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)
chr8_-_37822813	21.466		ADRB3	adrenergic, beta-3-, receptor
chr14_+_92789536	21.384	NM_153647	SLC24A4	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr19_+_35630391	21.366	NM_005031	FXYD1	FXYD domain containing ion transport regulator 1
chr17_+_77030471	21.299	NM_198593	C1QTNF1	C1q and tumor necrosis factor related protein 1
chr14_+_101193275	21.188		DLK1	delta-like 1 homolog (Drosophila)
chr11_-_35440514	21.156		SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr16_-_19896105	20.641	NM_016235	GPRC5B	G protein-coupled receptor, family C, group 5, member B
chr5_-_73937248	20.484	NM_003633	ENC1	ectodermal-neural cortex 1 (with BTB-like domain)
chr6_-_39197225	20.412	NM_003740	KCNK5	potassium channel, subfamily K, member 5
chr1_+_203595929	20.348		ATP2B4	ATPase, Ca++ transporting, plasma membrane 4
chr1_+_111833473	20.229	NM_021797 NM_201653	CHIA	chitinase, acidic
chr8_-_145701717	20.031	NM_003923	FOXH1	forkhead box H1
chrX_+_102631408	20.029		NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1
chr17_-_76975932	19.968	NM_005567	LGALS3BP	lectin, galactoside-binding, soluble, 3 binding protein
chr14_+_96858436	19.950	NM_152327	AK7	adenylate kinase 7
chr17_+_48503607	19.787		ACSF2	acyl-CoA synthetase family member 2
chr16_+_67226027	19.761	NM_001950	E2F4	E2F transcription factor 4, p107/p130-binding
chr22_-_46449972	19.755	NM_018280	C22orf26	chromosome 22 open reading frame 26
chr7_-_64023444	19.700
chrX_+_102631267	19.686	NM_206915 NM_206917	NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1
chr5_-_43412417	19.617	NM_148672	CCL28	chemokine (C-C motif) ligand 28
chr16_-_28550324	19.487	NM_001042483 NM_012385	NUPR1	nuclear protein, transcriptional regulator, 1
chr14_+_92788924	19.367	NM_153648	SLC24A4	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr8_-_42065037	19.281		PLAT	plasminogen activator, tissue
chr3_-_12200850	19.239	NM_003256	TIMP4	TIMP metallopeptidase inhibitor 4
chr1_+_153600859	19.142	NM_006271	S100A1	S100 calcium binding protein A1
chr14_+_101193313	19.051		DLK1	delta-like 1 homolog (Drosophila)
chr1_+_203596222	18.987		ATP2B4	ATPase, Ca++ transporting, plasma membrane 4
chr1_+_203595897	18.977	NM_001001396 NM_001684	ATP2B4	ATPase, Ca++ transporting, plasma membrane 4
chr6_+_31982538	18.746	NM_001242823 NM_001252204 NM_007293 NM_001002029	LOC100293534 C4A C4B	complement C4-B-like complement component 4A (Rodgers blood group) complement component 4B (Chido blood group)
chr10_-_128077011	18.680		ADAM12	ADAM metallopeptidase domain 12
chr14_-_76447445	18.671		TGFB3	transforming growth factor, beta 3
chr1_-_23810627	18.476		ASAP3	ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr3_+_14989076	18.364	NM_003298	NR2C2	nuclear receptor subfamily 2, group C, member 2
chr22_+_22735202	18.349
chr1_-_243418675	18.047	NM_001042404 NM_001042405 NM_014812	CEP170	centrosomal protein 170kDa
chr16_+_2588000	18.045		PDPK1	3-phosphoinositide dependent protein kinase-1
chr10_+_88718287	17.878	NM_003087	SNCG	synuclein, gamma (breast cancer-specific protein 1)
chr22_+_26565623	17.818		SEZ6L	seizure related 6 homolog (mouse)-like
chr9_-_113800243	17.756	NM_001401 NM_057159	LPAR1	lysophosphatidic acid receptor 1
chr22_+_30792929	17.615	NM_001204204 NM_012429 NM_033382	SEC14L2	SEC14-like 2 (S. cerevisiae)
chr9_-_34710062	17.516	NM_002989	CCL21	chemokine (C-C motif) ligand 21
chr15_-_40213087	17.436	NM_007223	GPR176	G protein-coupled receptor 176
chr1_+_154377847	17.374		IL6R	interleukin 6 receptor
chr19_+_46806855	17.308	NM_152794	HIF3A	hypoxia inducible factor 3, alpha subunit
chr10_+_124320180	17.128	NM_004406 NM_007329 NM_017579	DMBT1	deleted in malignant brain tumors 1
chr17_+_77893155	17.060
chr22_+_41763299	16.956	NM_001145398	TEF	thyrotrophic embryonic factor
chr1_-_22263676	16.947	NM_005529	HSPG2	heparan sulfate proteoglycan 2
chr1_+_150255228	16.934	NM_144697	C1orf51	chromosome 1 open reading frame 51
chr9_+_27109138	16.496	NM_000459	TEK	TEK tyrosine kinase, endothelial
chr1_+_1981902	16.425	NM_002744	PRKCZ	protein kinase C, zeta
chr9_+_124030455	16.290		GSN	gelsolin
chr6_+_31949800	16.245	NM_001242823 NM_001252204 NM_007293 NM_001002029	LOC100293534 C4A C4B	complement C4-B-like complement component 4A (Rodgers blood group) complement component 4B (Chido blood group)
chr8_+_55370494	16.206	NM_022454	SOX17	SRY (sex determining region Y)-box 17
chr17_+_48503518	16.056	NM_025149	ACSF2	acyl-CoA synthetase family member 2
chr6_+_39760772	15.953	NM_015345	DAAM2	dishevelled associated activator of morphogenesis 2
chr10_+_17270469	15.865		VIM	vimentin
chr19_+_46801632	15.832	NM_022462 NM_152796	HIF3A	hypoxia inducible factor 3, alpha subunit
chr14_+_69951396	15.828	NM_001161498	PLEKHD1	pleckstrin homology domain containing, family D (with coiled-coil domains) member 1
chr14_+_101193190	15.730	NM_003836	DLK1	delta-like 1 homolog (Drosophila)
chrX_-_40506666	15.702		CXorf38	chromosome X open reading frame 38
chr9_-_130617009	15.688	NM_000118 NM_001114753	ENG	endoglin
chr1_-_201342318	15.655		TNNT2	troponin T type 2 (cardiac)
chr22_-_19109718	15.576		DGCR2	DiGeorge syndrome critical region gene 2
chrX_-_154114431	15.555	NM_019863	F8	coagulation factor VIII, procoagulant component
chr6_+_132129195	15.534		ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1
chr7_+_116165089	15.501		CAV1	caveolin 1, caveolae protein, 22kDa
chr11_+_114166534	15.296	NM_006169	NNMT	nicotinamide N-methyltransferase
chr19_+_50380681	15.280	NM_001168222 NM_024682	TBC1D17	TBC1 domain family, member 17
chr1_+_54359859	15.261	NM_000792 NM_001039715 NM_001039716 NM_213593	DIO1	deiodinase, iodothyronine, type I
chr11_-_6341708	15.202	NM_145040	PRKCDBP	protein kinase C, delta binding protein
chr14_+_85996454	15.002	NM_013231	FLRT2	fibronectin leucine rich transmembrane protein 2
chr17_+_7184978	14.906	NM_001042	SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4
chr19_+_58790306	14.716	NM_021089	ZNF8	zinc finger protein 8
chr1_-_16344438	14.706		HSPB7	heat shock 27kDa protein family, member 7 (cardiovascular)
chr2_-_216300444	14.617		FN1	fibronectin 1
chr3_-_42305438	14.612	NM_001174138	CCK	cholecystokinin
chr16_-_86542463	14.568		LOC400550	uncharacterized LOC400550
chr20_+_42194736	14.355	NM_016276	SGK2	serum/glucocorticoid regulated kinase 2
chr11_-_2159472	14.199		IGF2	insulin-like growth factor 2 (somatomedin A)
chr1_-_173174611	14.174		TNFSF4	tumor necrosis factor (ligand) superfamily, member 4
chr19_+_55281262	14.154	NM_014218	KIR2DL1 KIR2DS4	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
chr7_-_97619350	14.106	NM_006188	OCM2	oncomodulin 2
chr1_-_32264215	14.019		SPOCD1	SPOC domain containing 1
chr8_+_38243958	14.000	NM_001199659 NM_144652	LETM2	leucine zipper-EF-hand containing transmembrane protein 2
chr7_-_44105162	13.965	NM_000290	PGAM2	phosphoglycerate mutase 2 (muscle)
chr10_+_17271859	13.942		VIM	vimentin
chr6_-_30043547	13.836	NM_170769 NM_025236	RNF39	ring finger protein 39
chr20_+_34742656	13.817	NM_012156	EPB41L1	erythrocyte membrane protein band 4.1-like 1
chr15_-_35087748	13.775	NM_005159	ACTC1	actin, alpha, cardiac muscle 1
chr15_+_42867708	13.743	NM_020759	STARD9	StAR-related lipid transfer (START) domain containing 9
chr19_-_14016908	13.610	NM_024323	C19orf57	chromosome 19 open reading frame 57
chr6_+_14117486	13.524	NM_001251901	CD83	CD83 molecule
chr21_+_27107322	13.503	NM_002040	GABPA	GA binding protein transcription factor, alpha subunit 60kDa
chr19_-_41356193	13.239	NM_000762	CYP2A6	cytochrome P450, family 2, subfamily A, polypeptide 6
chr3_+_9791602	13.210	NM_002542 NM_016819 NM_016820 NM_016821 NM_016826 NM_016827 NM_016828 NM_016829	OGG1	8-oxoguanine DNA glycosylase
chr1_+_154378044	13.205		IL6R	interleukin 6 receptor
chr1_-_112046742	13.198	NM_000677 NM_020683	ADORA3	adenosine A3 receptor
chr2_+_203499819	13.193	NM_173511	FAM117B	family with sequence similarity 117, member B
chr10_-_128077072	13.190	NM_003474 NM_021641	ADAM12	ADAM metallopeptidase domain 12
chr7_-_5569200	13.153		ACTB	actin, beta
chr1_-_23810721	13.147	NM_001143778 NM_017707	ASAP3	ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr3_-_126076057	13.088	NM_014079	KLF15	Kruppel-like factor 15
chr8_+_17780492	13.070		PCM1	pericentriolar material 1
chr13_+_113622758	13.066		MCF2L	MCF.2 cell line derived transforming sequence-like
chr15_-_90347173	13.049		ANPEP	alanyl (membrane) aminopeptidase
chr11_+_1244292	13.044	NM_002458	MUC5B	mucin 5B, oligomeric mucus/gel-forming
chr16_+_20420854	13.036	NM_017888	ACSM5	acyl-CoA synthetase medium-chain family member 5
chr20_+_24450269	13.000		SYNDIG1	synapse differentiation inducing 1
chr8_+_22022644	12.993	NM_001199 NM_006129	BMP1	bone morphogenetic protein 1
chr8_+_22022677	12.959		BMP1	bone morphogenetic protein 1
chr16_+_2587951	12.933	NM_002613 NM_031268	PDPK1	3-phosphoinositide dependent protein kinase-1
chr17_-_15902907	12.929	NM_001042697 NM_001042698	ZSWIM7	zinc finger, SWIM-type containing 7
chr14_+_95047792	12.854		SERPINA5	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr1_-_151345156	12.853	NM_003944	SELENBP1	selenium binding protein 1
chr19_-_40440532	12.840	NM_003890	FCGBP	Fc fragment of IgG binding protein
chr19_-_33716609	12.797	NM_019849	SLC7A10	solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10
chr3_-_12200339	12.670		TIMP4	TIMP metallopeptidase inhibitor 4

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.37	4.41e-08	GO:0032501	multicellular organismal process
1.45	1.48e-07	GO:0032502	developmental process
1.51	2.46e-07	GO:0048856	anatomical structure development
1.51	1.70e-06	GO:0048731	system development
1.44	3.44e-06	GO:0007275	multicellular organismal development
1.23	5.23e-06	GO:0065007	biological regulation
1.70	2.89e-05	GO:0009653	anatomical structure morphogenesis
1.56	9.49e-05	GO:0030154	cell differentiation
1.55	9.59e-05	GO:0048869	cellular developmental process
1.26	1.36e-04	GO:0050896	response to stimulus
1.36	4.83e-04	GO:0023052	signaling
1.20	1.20e-03	GO:0050789	regulation of biological process
1.12	1.33e-03	GO:0009987	cellular process
1.52	1.69e-03	GO:0048583	regulation of response to stimulus
1.20	3.57e-03	GO:0050794	regulation of cellular process
1.45	3.68e-03	GO:0042221	response to chemical stimulus
1.46	3.84e-03	GO:0065008	regulation of biological quality
1.30	5.16e-03	GO:0051716	cellular response to stimulus
1.58	6.25e-03	GO:0009966	regulation of signal transduction
6.03	7.05e-03	GO:0035272	exocrine system development
1.33	8.93e-03	GO:0007165	signal transduction
1.60	1.16e-02	GO:0051239	regulation of multicellular organismal process
7.45	1.17e-02	GO:0044246	regulation of multicellular organismal metabolic process
20.50	1.24e-02	GO:0048755	branching morphogenesis of a nerve
1.52	1.29e-02	GO:0023051	regulation of signaling
2.47	1.42e-02	GO:0008361	regulation of cell size
2.87	1.66e-02	GO:0001525	angiogenesis
8.44	1.77e-02	GO:0010712	regulation of collagen metabolic process
1.45	2.82e-02	GO:0048513	organ development
2.21	3.51e-02	GO:0032535	regulation of cellular component size
1.41	3.61e-02	GO:0048523	negative regulation of cellular process
2.30	4.15e-02	GO:0001944	vasculature development
1.39	4.45e-02	GO:0048519	negative regulation of biological process
6.31	4.82e-02	GO:0007431	salivary gland development
6.31	4.82e-02	GO:0071825	protein-lipid complex subunit organization
6.31	4.82e-02	GO:0071827	plasma lipoprotein particle organization

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
2.22	1.18e-12	GO:0044421	extracellular region part
2.07	2.93e-12	GO:0031226	intrinsic to plasma membrane
2.05	1.08e-11	GO:0005887	integral to plasma membrane
1.72	4.42e-10	GO:0005576	extracellular region
1.67	1.77e-09	GO:0044459	plasma membrane part
2.20	5.11e-09	GO:0005615	extracellular space
2.50	5.74e-06	GO:0031012	extracellular matrix
2.61	1.11e-05	GO:0005578	proteinaceous extracellular matrix
2.42	2.24e-05	GO:0009986	cell surface
1.33	5.75e-05	GO:0005886	plasma membrane
1.31	1.32e-04	GO:0071944	cell periphery
1.68	4.02e-04	GO:0000267	cell fraction
1.74	1.87e-03	GO:0005626	insoluble fraction
1.72	4.67e-03	GO:0005624	membrane fraction
2.03	7.72e-03	GO:0043005	neuron projection
2.58	1.30e-02	GO:0044297	cell body
2.53	2.50e-02	GO:0043025	neuronal cell body
1.60	3.46e-02	GO:0042995	cell projection

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.78	7.70e-05	GO:0005102	receptor binding
1.19	1.69e-03	GO:0005515	protein binding
2.84	4.71e-03	GO:0008083	growth factor activity
4.56	2.44e-02	GO:0019825	oxygen binding
10.25	2.85e-02	GO:0008191	metalloendopeptidase inhibitor activity
10.25	2.85e-02	GO:0048551	metalloenzyme inhibitor activity
2.51	3.32e-02	GO:0005126	cytokine receptor binding
2.20	3.85e-02	GO:0032403	protein complex binding